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. Author manuscript; available in PMC: 2018 Sep 26.
Published in final edited form as: Org Biomol Chem. 2017 Sep 26;15(37):7770–7782. doi: 10.1039/c7ob01448a

Fig.4. Attempted modification in cPT scaffold to improve solubility of cPT 34.

Fig.4

Each cPT was synthesized starting from the corresponding amino acids: Asn for 34 and Dab for 35. Designation of “poor” and “good” solubility was based on behavior of cPT in PBS buffer or PBS buffer with 5% DMSO.