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. Author manuscript; available in PMC: 2018 Oct 7.
Published in final edited form as: J Theor Biol. 2017 May 18;430:245–282. doi: 10.1016/j.jtbi.2017.05.013

Figure 2.

Figure 2

Desmoplastic tumor evolution with regionally varied ℱBn. Time progression from left to right for t = 1, 5, 10, 15, and 20, and plots are made for a cross section of the index plane j = k = 58. First row: tumor viable species ϕ∼V, dead species ϕ∼D, and ECM species ϕ∼E. The overall tumor pressure is labeled by pα. Second row: diffusible substances driving the tumor evolution, including oxygen (O2), glucose (Glu), carbon dioxide (CO2), bicarbonate (Bic), lactate (Lac), and hydrogen ions (H+). Third row: Concentration of myfibroblasts (myF), tumor growth factors (TGF), and matrix degrading enzymes (MDE). Fourth row: corresponding density of blood vasculature (Bn), lymphatic vasculature (Ln), and tumor angiogenic factors (TAF).