Table 5.
Dimensionless Parameter | Biological Representation | Scaling Factor* | Value Assigned | ||
---|---|---|---|---|---|
|
Mobility of cell species | ℳ | 0.1 | ||
|
Motility of the solid phase (cells) |
|
Computed† | ||
|
Motility of the tumor cell phase |
|
10.0 | ||
|
Motility of the ECM phase |
|
10.0 | ||
|
Motility of the healthy host cell phase |
|
10.0 | ||
|
Motility of the fluid phase (interstitial fluid) |
|
1.0 | ||
|
Chemotaxis coefficient of ECs |
|
1.0 | ||
|
Haptotaxis coefficient of ECs |
|
1.0 | ||
|
Minimum haptotaxis coefficient of ECs |
|
1.0 | ||
|
Chemotaxis coefficient of LECs |
|
1.0 | ||
|
Haptotaxis coefficient of LECs |
|
1.0 | ||
|
Minimum haptotaxis coefficient of LECs |
|
1.0 |
For example, .
The solid phase motility is computed from , , and using Eq. (3.7.25) by replacing with .
Nondimensionalized chemotaxis and heptotaxis coefficients are set to 1 as an initial value in this study. A wider range of values will be tested and analyzed in future work.