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. 2017 Sep 1;471(4):553–557. doi: 10.1007/s00428-017-2225-9

Table 1.

Summary of previously reported cases of composite pheochromocytoma with immature neuroblastoma component including the two cases reported in this study

Case number Reference Age (years)/sex Associated syndromes Location Metastasis Treatment N-MYC amplification Follow-up
1 Wahl 1943 [2] 4/M None Mediastinum Yes Radiation N/A Died (8-month follow-up)
2 Franquemont 1994 [3] 49/M None Adrenal-left No Surgery N/A No evidence of disease after 1 year
3 Franquemont 1994 [3] 38/M None Adrenal-right Yes Surgery and chemoradiation N/A Died 3 months after diagnosis
4 Candanedo-Gonzalez 2001 [4] 56/F None Adrenal-right No Surgery N/A Asymptomatic at 24 months post-op
5 Tatekawa 2006 [5] 5/M None Adrenal-left No Surgery N/A Unknown
6 Comstock 2009 [6] 17/M NF1 Adrenal-laterality unspecified No Unknown Non-amplified Alive (follow-up date unknown)
7 Steen 2014 [7] 46/M None Adrenal-left No Surgery N/A Asymptomatic and normotensive at 6 months post-op
8 Current study 57/M NF1 Adrenal-left No Surgery Non-amplified Asymptomatic and normotensive (6 months post-op)
9 Current study 5/M None Adrenal-left Yes Surgery, chemoradiation, SCT Amplified Died 2 years after diagnosis

NF 1 neurofibromatosis type 1, SCT stem cell transplant