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. 2017 Sep 22;8:729. doi: 10.3389/fphys.2017.00729

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Copyright © 2017 Sun, Li, Liu, Wei, Pan, Fan and Han.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of XYS post-treatment on follicle development of the ovary. (A) Representative HE staining images of rat ovarian tissue (a1,a2). The area within the rectangle in each image in left panel is enlarged and presented right, exhibiting the representative images of primordial follicle (b1, dotted arrow), primary follicle (b1, solid arrow), secondary follicle (b2), antral follicle (b3), atretic follicle (b4), and cystic follicle (b5), respectively. (B) Statistical result of the percentage of the follicles in different development stages in various groups. Results are presented as mean ± SE. ^*P < 0.05 vs. Control group; ^#P < 0.05 vs. CUMS group; ^†P < 0.05 vs. CUMS+NS group, n = 3.