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. 2017 Sep 26;7:12329. doi: 10.1038/s41598-017-12190-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Finite element model of C. elegans body deformed by a 10 µm diameter sphere with a 0.49 µN stimulus. (B) A heat map distribution of SED at the receptor location (ie. 0.6 µm below surface) after 0.49 µN mechanical load. The y axis is the location of the probe as it was indented, while the z axis is the longitudinal and x axis transverse direction of the worm body. Each layer is a slice of 0.2 µm in depth (y axis) and the plane is 4 µm × 4 µm (x and z axis respectively). (C) At the depth of 0.5–0.7 µm where the neurites of the touch neurons reside the SED distribution along the length of the worm (z direction) within a ROI of 200 nm after force stimulation of 0.064 µN, 0.49 µN, or 1.09 µN with a 10 µm diameter probe or 1.5 µN with a 15 µm diameter probe (red line) respectively.