Fig. 4.

Rheumatoid factor and TLR expression. (a) IgG rheumatoid factor (IgG-RF) measured in serum collected at termination, (b) TLR 2 (percent) and (c) TLR 2 (mean fluorescence intensity (MFI)) measured in splenocytes, from female (closed symbols, n = 5) and male (open symbols, n = 5) DA-rats exposed to a single intradermal pristane injection (200 μl), feed containing 4000 mg/kg pristane, or feed containing 0 (control), 40, 400 and 4000 mg/kg of a broad MOSH mixture. The symbols represent the value for the individual animals while the lines represent the group median value. Two-way ANOVA results (treatment and sex as the two factors) are stated in the figures if statistically significant (p < 0.05).