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Arthritis incidence, maximum score and day of onset in female Dark Agouti rats intradermally (i.d) injected day 0 with 200 μl pristane (n = 6) or physiological saline buffer (n = 6) and monitored twice a week for 40 days.
| Treatment | Arthritis incidence | Maximum scorea | Day of onset |
|---|---|---|---|
| Pristane i.d. | 6/6 | 7, 11, 11, 10, 10, 9 | 12, 12, 8, 8, 12, 8 |
| Saline i.d. | 0/6 | 0 | 0 |
Rats with arthritic score >10 and/or weight reduction >10% per week were sacrificed for animal welfare reasons.
