Fig. 1.

Photomicrograph of liver tissues after aflatoxin B1 treatments with hematoxylin and eosin staining. Representative slides are shown for each of the four exposure groups: (A) control showing: (1) portal triad and (2) central vein (B) 0.25 mg/kg AFB1 showing: (1) microvesicles, (2) macrovesicles and (3) portal triad (C) 0.50 mg/kg AFB1 showing: (1) inflammatory cells, (2) portal triad, (3) central vein and (4) microvesicles and (D) 1.0 mg/kg AFB1 showing (1) inflammatory cells, (2) hepatic artery, (3) portal vein and (4) bile duct. Compared to the control group, pathology of the 0.25 mg/kg was minimal. In the 0.5 mg/kg group, sinusoid congestion was evident along with inflammatory infiltration around the portal triad. In the highest dose group, inflammation extended to the central vein and the portal triad along with profileration of the bile ductules.