Fig. 4.

Effect of both ITAE and SDAE administration on the mRNA expression of granzyme B and perforin in splenic NK cells under normal and noise stressed groups. (A) Lane 1. DNA ladder (100 bp), 2. Control + No stress, 3. No stress + ITAE treated, 4. No stress + SDAE treated 5. Noise stress, 6. Noise stress + ITAE treated, 7. Noise stress + SDAE treated. (B) PCR products were quantified by densitometric scanning and granzyme B (B1) and perforin (B2) expression was normalized relative to the steady-state expression of GAPDH used as internal control. Data are expressed as mean ± SD (n = 9). Bars labeled with different letters represent a statistical difference at (p < 0.05).