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DIO inhibits ADR-induced oxidative stress.
(A) Flow cytometric evaluation of H2DCFDA stained-negative control, positive control and ADR-treated cells at various time points. (B) Effect of DIO on ADR (3 h) induced ROS in cultured RPE cells, as measured by flow cytometry. (C) The content of intracellular GSH after treatment with ADR and DIO for 12 h. The data represent the mean ± SD (n = 4), *P < 0.05, **P < 0.01, ***P < 0.001 (ADR vs. control), ††P < 0.01 (DIO + ADR vs. ADR).
