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. 2017 Sep 26;19:211. doi: 10.1186/s13075-017-1402-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — HM71224 prevents skin lesion progression. Skin lesions were observed in vehicle-treated mice around the nose or eyes (arrows show representative skin lesions) (a, b) compared with HM71224-treated MRL/lpr mice (c, d). e Skin lesion severity score was 1.4 ± 0.5 (mean ± SEM) in vehicle-treated mice, whereas no skin lesions developed in HM71224-treated MRL/lpr mice (P < 0.001) at 28 weeks of age (n = 11 per vehicle-treated group, n = 12 per HM71224-treated group)