Table 2.
Receiver-operating characteristic (ROC) curve analysis for the discrimination between patients with unexplained infertility and control group
| ROC Index | Endometrial thickness | Subendometrial RI | ανβ3-integrin score |
|---|---|---|---|
| AUC | 0.966 | 0.918 | 0.880 |
| 95% CI of AUCŦ | 0.932 to 1.0 | 0.854 to 0.981 | 0.799 to 0.961 |
| P value* | <0.0001 | <0.0001 | <0.0001 |
| Youden index J | 0.80 | 0.71 | 0.74 |
| Cut-off criterion | ≤7 mm | >0.65 | Score 0 |
| Sensitivity (%) | 82.9 | 74.3 | 74.3 |
| 95% CI of sensitivity | 66.4–93.4 | 56.7–87.5 | 56.7–87.5 |
| Specificity | 97.1 | 97.1 | 100.0 |
| 95% CI of Specificity | 85.1–99.9 | 85.1–99.9 | 90.0–100.0 |
| Positive predictive value (PPV) % | 96.7 | 96.3 | 100.0 |
| 95% CI of PPV | 82.8–99.9 | 81.0–99.9 | 86.8–100.0 |
| Negative predictive value (NPV) % | 85.0 | 79.1 | 79.5 |
| 95% CI of NPV | 70.2–94.3 | 64.0–90.0 | 64.7–90.2 |
ŦAUC, area under the curve, PPV, positive predictive value; NPV, negative predictive value
*DeLong method