Table 2.
Mean changes in the level of nicotine, PG and glycerol in surface samples from baseline to product use conditions (μg/cm2).
| Condition | LOQ (μg/cm2) | Group I | Group II | Group III | Group IV |
|---|---|---|---|---|---|
| (n = 9) | (n = 9) | (n = 9) | (n = 10) | ||
| Nicotine | 0.001 | ||||
| Pre-specified | 0.001 ± 0.002 | NC | n/a | n/a | |
| Ad libitum | NC | NC | NC | 0.001 ± 0.002 | |
| Propylene glycol | 0.019 | ||||
| Pre-specified | 0.02 ± 0.01 | 0.005 ± 0.010 | n/a | n/a | |
| Ad libitum | NC | 0.01 ± 0.01 | NC | NC | |
| Glycerol | 0.02 | ||||
| Pre-specified | NC | 0.07 ± 0.02 | n/a | n/a | |
| Ad libitum | 0.02 ± 0.01 | NC | 0.35 ± 0.12 | 0.00 ± 0.00 |
Note: Values are means ± standard deviations of four surface samplers placed in the EC. n is the number of study participants present in the EC for each group. NC: not calculated (values < LOQ). Statistically significant (p-value < 0.05) differences between baseline and product use condition are highlighted in bold font. n/a: not applicable.