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Induction of apoptosis (%) by extracts in HaCaT, immortalized human keratinocytes, and HNSCC cells. Rapidly proliferating HaCaT and three HNSCC cells; SCC-61, SQ-20B and OSCC-3, were exposed to IC50 concentrations of EGCG and etoposide, GT and MT (AT: IC20 for SCC-61 and OSCC-3). Values are means ± SD from three independent experiments performed in triplicate. *Statistically different from PBS (P < 0.05) for either alive or apoptotic cells. □ alive cells, ■ apoptotic cells.
