. 2016 Feb 1;3:269–278. doi: 10.1016/j.toxrep.2016.01.013

Table 1.

Cytotoxicity and inhibition of proliferation of HaCaT, SCC-61, SQ-20B and OSCC-3 cells after 48 h exposure to (−) epigallocatechin-3-gallate (EGCG), and hot water extracts of Camellia sinensis (GT), Ilex paraguariensis (MT) and Ardisia compressa (AT).^*

HaCaT
	EGCGm (μM)	GT (μM eq. (+) catechin)	MT (μM eq. (+) catechin)	AT (μM eq. (+) catechin)
IC₅₀	116.1^a	99.6^a	99.9^a	504.5^b
GI₅₀	100.0^a,b	85.4^a	84.2^a	125.0^b
TGI	177.9^b	191.5^b	94.7^a	239.0^c
LC₅₀	237.1^b	270.8^c	118.7^a	>222.3^b

SCC-61
	EGCG (μM)	GT (μM eq. (+) catechin)	MT (μM eq. (+) catechin)	AT (μM eq. (+) catechin)
IC₅₀	123.0^b	132.6^b	74.8^a	453.4^c
GI₅₀	79.4^a	107.8^a,b	94.3^a	235.3^c
TGI	133.4 ^b	135.0^b	105.8^a	>295.9^c
LC₅₀	177.8 ^b	170.9^b	118.7^a	>295.9^c

SQ-20B
	EGCG (μM)	GT (μM eq. (+) catechin)	MT (μM eq. (+) catechin)	AT (μM eq. (+) catechin)
IC₅₀	81.3^a	152.2^b	213.9^c	355.2^d
GI₅₀	100.0^a	170.8^b	186.4^b	296.0^c
TGI	199.5^a	303.7^b	209.1^a	>592.0^c
LC₅₀	251.2^a	340.8^b	263.2^a	>592.0^c

OSCC-3
	EGCG (μM)	GT (μM eq. (+) catechin)	MT (μM eq. (+) catechin)	AT (μM eq. (+) catechin)
IC₅₀	166.0^b	184.3^b	266.0^c	112.7^a
GI₅₀	141.3^b	170.9^b	237.1^c	73.0^a
TGI	173.8^b	191.5^b	266.0^c	148.5^a
LC₅₀	251.1^b	227.7^b	298.7^c	166.4^a

See Section 2 for details. Values are the average of three independent experiments performed in triplicate. Different letters in a row, per type of cell, are statistically different (P < 0.05).