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. 2016 Mar 5;3:357–363. doi: 10.1016/j.toxrep.2016.02.003

Fig. 1.

Fig. 1

(A) body weight of sham and ovx mice 8 weeks after operation. The average weights of both group before operation were almost the same (20 ± 0.5 g). (B) Survival plots of sham and ovx mice after DOXY injection. Survival rates of sham and ovx mice treated with saline + DOXY (S + D) or apocynin + DOXY (A + D) are presented. *p < 0.05. All ovx mice (n = 10) died within 48 h after saline and DOXY (240 mg/kg) injection. Survival rate of sham mice (n = 10) at 72 h was better than that of ovx mice. (C) Changes in ALT levels in sham or ovx mice treated with saline + saline (S + S), saline + DOXY (S + D) or apocynin + DOXY (A + D) at 0, 3, 6, 9 and 24 h after DOXY injection. *p < 0.05, **p < 0.01 vs sham S + D mice. #p < 0.05, ##p < 0.01 vs ovx A + D mice. Эp < 0.05, ЭЭp < 0.01 vs ovx S + S mice. Data are average ± SE. sham S + S (n = 2), sham S + D (n = 13), sham A + D (n = 8), ovx S + S (n = 2), ovx S + D (n = 13), ovx A + D (n = 7).