Hematoxylin and eosin tissue staining at 3 h after DOXY injection with/without apocynin pretreatment. Sham groups; saline + saline (S + S) (A), apocynin + saline (A + S) (B), saline + DOXY (S + D) (C), apocynin + DOXY (A + D) (D). Ovx groups; saline + saline (S + S) (E), apocynin + saline (A + S) (F), saline + DOXY (S + D) (G), apocynin + DOXY (A + D) (H). Arrows indicate denatured hepatocytes. Normal hepatocyte areas were quantified (I). *p < 0.05, **p < 0.01 vs S + S mice.