(A) Changes in Nox activity in livers obtained from sham or ovx mice at 3 h after DOXY injection with/without apocynin pretreatment. Sham groups; saline + saline (S + S), saline + DOXY (S + D), apocynin + DOXY (A + D). Ovx groups; saline + saline (S + S), saline + DOXY (S + D), apocynin + DOXY (A + D). Data are average ± SE. *p < 0.05 vs ovx (S + D). #p < 0.05 vs sham (A + D). (B) Changes in IL-6 levels in plasma obtained from sham or ovx mice treated with saline (S + S), apocynin + saline (A + S), saline + DOXY (S + D) or apocynin + DOXY (A + D) at 3 and 6 h after DOXY injection. Data are average ± SE. *p < 0.05, **p < 0.01 vs ovx (S + S) or (S + A), #p < 0.05 vs sham (S + D).