Table 4.
Summary of comet assay results for CGTase and sodium sulfate.
| Males |
Females |
|||||
|---|---|---|---|---|---|---|
| % Tail DNA (Mean ± SEM) |
% Tail DNA (Mean ± SEM) |
|||||
| Dose (mg/kg) | Liver | Duodenum | Stomach | Liver | Duodenum | Stomach |
| CGTase | ||||||
| 0 | 5.6 ± 0.6 | 5.9 ± 0.8 | 11.2 ± 0.7 | 3.8 ± 0.8 | 4.5 ± 1.1 | 6.6 ± 1.8 |
| 1000 | 5.6 ± 0.5 | 5.2 ± 0.5 | 9.0 ± 1.14 | 3.5 ± 0.7 | 4.5 ± 0.8 | 6.6 ± 1.8 |
| 1500 | 5.9 ± 0.5 | 4.6 ± 0.5 | 11.7 ± 3.81 | 4.9 ± 0.4 | 3.5 ± 0.6 | 6.1 ± 1.7 |
| 2000 | 6.8 ± 0.4 | 4.6 ± 0.6 | 12.2 ± 2.31 | 4.5 ± 0.8 | 3.1 ± 0.5 | 7.9 ± 2.1 |
| EMS (150) | 15.4 ± 1.0* | 10.2 ± 0.9* | 16.5 ± 1.25* | 16.7 ± 2.3* | 11.1 ± 0.8* | 10.5 ± 1.0* |
| Sodium sulfate | ||||||
| 0 | 3.2 ± 0.5 | 3.7 ± 0.6 | 6.1 ± 0.9 | 8.4 ± 4.1 | 10.6 ± 1.4 | 3.2 ± 0.4 |
| 1000 | 2.9 ± 0.5 | 3.5 ± 0.5 | 3.7 ± 0.8 | 4.1 ± 1.0 | 7.8 ± 1.0 | 2.6 ± 0.2 |
| 1500 | 4.2 ± 0.5 | 2.7 ± 0.2 | 6.3 ± 1.5 | 4.1 ± 0.7 | 8.1 ± 2.0 | 3.1 ± 0.3 |
| 2000 | 3.1 ± 0.5 | 3.3 ± 0.5 | 3.7 ± 0.8 | 4.2 ± 0.3 | 11.7 ± 2.4 | 2.6 ± 0.2 |
| EMS (150) | 13.9 ± 1.0* | 9.4 ± 1.2* | 18.3 ± 2.7* | 13.5 ± 1.9* | 16.2 ± 2.4* | 10.1 ± 1.4* |
SEM = standard error of the mean; EMS = ethyl methanesulfonate.
*
p < 0.05.