Table 5c.
Relative White Blood Cell Differential Counts from Rats Exposed to CGTase for 90 days.
| Dose Level (mg/kg/day) | Sex | Lymphocytes% ± SD | Monocytes% ± SD | Eosinophils% ± SD | Basophils % ± SD |
Leukocytes% ± SD | Neutrophils% ± SD |
|---|---|---|---|---|---|---|---|
| 0.0 | M | 81.6 ± 1.5 (10)a |
3.2 ± 0.7 (10) | 1.2 ± 0.4 (10) | 1.7 ± 0.7 (10) |
1.1 ± 0.2 (10) |
11.2 ± 1.7 (10) |
| 250 | M | 78.1 ± 5.7 (8) |
3.1 ± 0.7 (8) | 2.7 ± 3.3 (8) |
1.4 ± 0.3 (8) |
0.9 ± 0.3 (8) |
13.7 ± 3.3 (8) |
| 500 | M | 77.3 ± 4.0 (6) |
3.2 ± 0.6 (6) | 1.5 ± 0.6 (6) |
1.4 ± 0.1 (6) |
1.0 ± 0.3 (6) |
15.7 ± 4.6 (6) |
| 1000 | M | 80.6 ± 2.2 (9) |
3.3 ± 0.7 (9) | 1.6 ± 0.6 (9) |
1.2 ± 0.3 (9) |
1.2 ± 0.3 (9) |
12.0± 2.6 (9) |
| 0.0 | F | 79.8 ± 4.8 (9) |
3.2 ± 0.9 (9) | 2.3 ± 2.0 (9) |
1.4 ± 0.3 (9) |
1.0 ± 0.3 (9) |
12.3 ± 3.7 (9) |
| 250 | F | 82.7 ± 3.3 (8) |
2.9 ± 0.7 (8) |
1.6 ± 0.9 (8) |
1.3 ± 0.2 (8) |
1.2 ± 0.2 (8) |
10.4 ± 2.8 (8) |
| 500 | F | 79.9 ±4.9 (10) |
3.6 ± 0.1 (10) | 1.6 ± 0.7 (10) | 1.2 ± 0.2 (10) | 1.0 ± 0.4 (10) |
12.8 ± 4.1 (10) |
| 1000 | F | 79.3 ± 4.5 (9) |
3.4 ± 0.1 (9) | 2.3 ± 0.2 (9) |
1.2 ± 0.2 (9) |
0.1 ± 0.1 (9) |
12.7 ± 4.3 (9) |
SD = Standard deviation.
a
Number of samples.