Table 1.

Effects of Antituberculous Drugs on Male Reproductive Hormones in Rats.

	FSH (U/l)	LH (U/l)	Testosterone (U/l)
Control	0.18 ± 0.10	0.26 ± 0.10	1.57 ± 0.30
RIPE	0.06 ± 0.02*(66.7)[80]	0.14 ± 0.04*(46.2)[60]	0.90 ± 0.10*(42.8)[66.7]

NB: Result expressed as Mean ± SEM; n = 8; Control (DW, Distilled water, 1.6 ml); Values in parenthesis represent% change; (−) increase; (+) decrease. ⁽⁾ % mean, when compared with control distilled water; ^[] SEM when compared with control. ^*p < 0.05 change relative to control group. RIPE: Rifampicin + Isoniazid + Pyrazinamide + Ethambutol (92.5 mg/m² body surface area, body weight 60 kg man; Body Surface Area (BSA): man = 1.6; BSA rat (0.16 kg) = 0.025; k_m = Weight/BSA; k_m rat: 6; K_m man: 37). FSH = Follicle Stimulating Hormone; LH = Luteinizing Hormone.