Associations between crystallinity (percentage of TiO2 in rutile form) and bronchoalveolar lavage fluid parameter values at three days after intratracheal administration of indicated form of TiO2. (A) Differential neutrophil ratio, (B) Total protein content, (C) Lactate dehydrogenase (LDH). Values are presented as the average of the difference between the value for the 2-mg/kg group and that of the control group. Percentage of TiO2 in rutile form: AMT-100, 0%; MT-150AW, 100%; TTO-S-3, 100%; TTO-S-3 (Coated), 100%; P25, 20%; MP-100, 100%; FTL-100, 100%.