Table 2.
Comparison of functional and morphologic changes from time of switch to 24 months.
| Central macular thickness (μm) | Baseline N = 44 |
Month 3 N = 44 |
p | Month 6 N = 44 |
p | Month 12 N = 44 |
p | Month 24 N = 38 |
p |
|---|---|---|---|---|---|---|---|---|---|
| ETDRS | 64.4 ± 13.1 | 67.6 ± 12.3 | 0.002 | 67.3 ± 11 | 0.005 | 64.8 ± 13 | 0.6 | 61.4 ± 13.8 | 0.2 |
| Central macular thickness (μm) | 313 ± 13 | 312 ± 91 | 0.2 | 312 ± 14.2 | 0.9 | 313 ± 13.9 | 0.9 | 305 ± 76 | 0.6 |
| Macular volume (mm3) | 7.70 ± 2.2 | 7.75 ± 0.16 | 0.8 | 7.8 ± 0.16 | 0.6 | 7.85 ± 0.16 | 0.4 | 7.8 ± 0.65 | 0.3 |
| PED height (μm) | 224.7 ± 18.5 | 198.5 ± 19.5 | 0.25 | 190 ± 17.3 | 0.5 | 224 ± 21 | 0.27 | 200 ± 19 | 0.14 |
| Subfoveal choroidal thickness (μm) | 179 ± 68 | 158 ± 67 | 0.2 | 174 ± 56 | 0.5 |
Data are mean ± SD unless indicated otherwise. p: continuous variables compared by independent samples t-test from baseline; BCVA: best-corrected visual acuity; ETDRS: Early Treatment Diabetic Retinopathy Scale; PED: pigment epithelial detachment.