Table 1.
Wound area (mm2) and wound contraction index (WCI; mm2/day) in diabetic rats treated with an ointment of Strychnos pseudoquina extract.
| Sal | VH | SS | ES5 | ES10 | ||
|---|---|---|---|---|---|---|
| F0 | Area | 160.3 ± 23.6 | 164.5 ± 13.6 | 165.3 ± 12.5 | 160 ± 12.1 | 166.5 ± 26.5 |
| WCI | 00.0 ± 00.0 | 00.0 ± 00.0 | 00.0 ± 00.0 | 00.0 ± 00.0 | 00.0 ± 00.0 | |
| F1 | Area | 115.4 ± 15.9 | 113.1 ± 13.9 | 109.6 ± 12.1 | 95.5 ± 11.3∗ | 76.8 ± 16.06∗ |
| WCI | 31.9 ± 17.4 | 39.7 ± 11.5 | 37.7 ± 13.1 | 32.4 ± 11.7 | 50.5 ± 12.6 | |
| F2 | Area | 30.0 ± 11.3 | 25.2 ± 12.9 | 35.3 ± 10.4 | 15.9 ± 8.8∗ | 16.8 ± 8.1∗ |
| WCI | 84.7 ± 9.3 | 88.3 ± 7.9 | 81.3 ± 9.1 | 89.1 ± 6.05 | 89.9 ± 5.5 | |
| F3 | Area | 10.4 ± 3.4 | 9.1 ± 4.1 | 8.18 ± 3.6 | 2.8 ± 1.7∗ | 3.2 ± 1.5∗ |
| WCI | 94.3 ± 5.3 | 94.0 ± 5.3 | 94.9 ± 2.6 | 98.0 ± 1.2 | 96.7 ± 2.4 |
Sal: 0.9% saline solution; VH: vehicle (lanolin cream); SS: silver sulfadiazine (cream) (10 mg/g); ES5 and ES10: S. pseudoquina 5% and 10%, respectively. F0 = intact tissue on day 0; F1, F2, and F3 = scar tissue on days 7, 14, and 21, respectively. Data are reported as mean and standard deviation (mean ± SD). ∗p ≤ 0.05, statistically different compared to Sal and VH.