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. 2017 Sep 13;2017:7180943. doi: 10.1155/2017/7180943

Figure 4.

Figure 4

The effects of NAC, CsA, and LY on MGO-induced HUVEC apoptosis. (a) HUVECs were pretreated with NAC (10 mM), CsA (1 μM), or vehicle control for 2 h, followed by stimulation with MGO (200 μM) for 24 h. (b) HUVECs were pretreated with PD (100 μM), PD (100 μM) + LY (50 μM), or vehicle control for 2 h, followed by stimulation with MGO (200 μM) for 24 h. Then cell apoptosis was analyzed by flow cytometry based on Annexin V-FITC/PI double staining. Representative images of cell population distribution are shown, and quantitative assessment of 3 independent experiments was performed. Data shown are mean ± SD and are expressed as fold changes. ∗∗P < 0.01 versus Con; ##P < 0.01 versus MGO; &&P < 0.01 versus MGO + PD.