Table 3.
Correlation of fasting serum log-leptin levels and clinical variables by univariable linear regression analyses among 62 elderly participants
| Items | Beta | P |
|---|---|---|
| Age (years) | 0.200 | 0.119 |
| Height (cm) | −0.161 | 0.213 |
| Body weight (kg) | 0.280 | 0.028* |
| BMI (kg/m2) | 0.417 | 0.001* |
| Waist circumference (cm) | 0.419 | 0.001* |
| Systolic blood pressure (mmHg) | 0.033 | 0.801 |
| Diastolic blood pressure (mmHg) | 0.162 | 0.209 |
| TCH (mg/dL) | 0.200 | 0.119 |
| TG (mg/dL) | 0.190 | 0.140 |
| HDL-C (mg/dL) | −0.035 | 0.790 |
| LDL-C (mg/dL) | 0.177 | 0.170 |
| Log-glucose (mg/dL) | −0.004 | 0.975 |
| BUN (mg/dL) | 0.255 | 0.046* |
| Creatinine (mg/dL) | 0.030 | 0.815 |
| GFR (mL/min) | −0.144 | 0.265 |
| Log-CRP (mg/dL) | 0.213 | 0.097 |
| Log-insulin (uIU/mL) | 0.436 | <0.001* |
| Log-HOMA-IR | 0.359 | 0.004* |
Data for glucose, CRP, insulin, HOMA-IR, and leptin levels showed skewed distributions and therefore were log-transformed before analysis. *P<0.05 was considered statistically significant after univariable linear analyses. HDL-C: High-density lipoprotein cholesterol, LDL-C: Low-density lipoprotein cholesterol, CRP: C-reactive protein, HOMA-IR: Homeostasis model assessment of insulin resistance, BUN: Blood urea nitrogen, BMI: Body mass index, TG: Triglycerides, TCH: Total cholesterol, GFR: Glomerular filtration rate