Skip to main content
. 2016 Feb 10;16(4):497–511. doi: 10.1177/1533034616630866

Figure 6.

Figure 6.

miR-139 repressed glioma cells proliferation through insulin-like growth factor type 1 receptor (IGF-1 R), associate of Myc-1 (AMY-1), and peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β). A, The knock down efficiency of synthetic RNAs (siRNAs) for IGF-1 R, AMY-1, and PGC-1β (n = 4). B, The glioma cells were transfected with effective siRNAs of IGF-1 R, associate of Myc-1 (AMY-1), and PGC-1β and detected the proliferation by methyl thiazolyl tetrazolium (MTT; n = 5). C, The glioma cells were transfected IGF-1 R, associate of Myc-1 (AMY-1), and PGC-1β in the condition of miR-139 overexpressed. The MTT assay was performed to tested proliferation of glioma cells (n = 5). D, The glioma cells were transfected siRNA of IGF-1 R with PGC-1β together and tested the proliferation (n = 5). Bars represent means ± SD, *P < .05, **P < .01, ***P < .001.