Figure 1.

Gelsolin is upregulated in radioresistant non–small cell lung cancer (NSCLC) cells. A, Clonogenic assays in assessing the sensitivity of radioresistant cells (A549/R and H460/R) and their parental cells to X-ray radiation. After radiation, cells were incubated for 10 days, and the number of colonies consisting of >50 cells was counted. Results are expressed as percentage of the control (nonirradiated cells). Quantitative real-time polymerase chain reaction (A; qRT-PCR) and Western blot analysis (C) of gelsolin expression levels in A549/R, H460/R, and their parental cells. Bar graphs represent means ± standard deviation (SD) from 3 independent experiments. *P < .05 between radioresistant and parental cells.