Table 2.
Multivariate Cox Analysis of Survival in Hilar Cholangiocarcinoma.
| Variables | HR | 95% CI | P Value |
|---|---|---|---|
| Sex: male vs female | 0.897 | 0.525-1.533 | .691 |
| Age: ≥65 vs <65 | 1.305 | 0.757-2.250 | .339 |
| Histologic grading: low, moderate vs high | 1.508 | 0.872-2.611 | .141 |
| Lymph node involvement: yes vs no | 1.461 | 0.879-2.427 | .143 |
| Perineural invasion: yes vs no | 1.230 | 0.709-2.133 | .461 |
| AQP1 expression: strong vs low | 2.288 | 1.364-3.831 | .002 |
| TNM stage: III/IV vs I/II | 12.105 | 5.289-27.706 | <.001 |
Abbreviations: AQP1, aquaporin 1; CI, confidence interval; HR, hazard ratio; TNM, tumor-node-metastasis.