Table 1.

Patient Demographics, Tumor Characteristics, and Treatment Characteristics of All Patients.^a

MLKL Expression
Parameter	n	Negative (%)	Positive (%)	P
Gender
Male	76	31	45	.538
Female	59	21	38
Age
<60	52	16	36	.143
≥60	83	36	47
TNM stage
I	16	4	12
II	75	29	46	.441
III	44	19	25
Differentiation
Well	9	2	7	.302
Middle	95	35	60
Poor	31	15	16
LNI
Negative	92	29	63	.015
Positive	43	23	20
LVI
Negative	112	43	69	.047
Positive	23	14	9
Tumor size
<5	90	30	60	.080
≥5	45	22	23
CEA
Normal	73	27	46	.691
High	62	25	37
Position
Left	50	19	31	.449
Transverse	6	6	13
Right	9	9	7
Sigmoid	18	18	32
Median age (range), years	67 (30-82)
Median OS (range), months	69.1 (5-95.3)
Median RFS (range), months	78.8 (6-92)

Abbreviations: CEA, carcino embryonie antigen; LNI, positive lymph node invasion; LVI, lymphovascular invasion; MLKL, mixed lineage kinase domain-like protein; OS, overall survival; RFS, recurrence-free survival; TNM, tumor node metastasis.

^an = 135.

^bBold type denotes statistical significance.