Table 4.

ROC-AUCs Curves for Individual and Combined Tumor Marker Assays for Stage I and Stage II to IV Endometrial Cancers.

Marker Combination	ROC-AUC	ROC-AUC
	Stage I	Stage II-IV
HE4	70.9% (65.4-86.0)	79.4% (75.6-92.1)
CA125	64.1% (57.5-70.6)	75.2% (67.0-85.4)
CA724	53.8% (47.7-64.3)	66.2% (57.8-73.1)
CA19-9	50.2% (43.7-58.2)	54.1% (43.1-65.1)
HE4 + CA125 + CA724	72.1% (70.1-81.2)	83.9% (79.0-95.7)
HE4 + CA125 + CA19-9	74.5% (70.2-82.1)	82.6% (85.6-96.1)
CA19-9 + CA125 + CA724	61.4% (56.1-69.8)	73.1% (71.0-87.2)
HE4 + CA19-9 + CA724	71.2% (71.0-82.3)	82.2% (80.1-93.8)
HE4 + CA125 + CA724 + CA19-9	76.8% (70.9-83.2)	89.9% (82.1-96.1)

Abbreviation: ROC-AUC, areas under the receiver operating characteristic curves.