Table 2.
Distribution of NAT2 genotypes and predicted acetylator phenotype (n = 96).
| Genotype | Number of subjects | Observed frequency (%) | Predicted phenotype |
|---|---|---|---|
| NAT2*5/*5 | 5 | 5.2 | Slow |
| NAT2*5/*6 | 16 | 16.7 | Slow |
| NAT2*5/*7 | 4 | 4.2 | Slow |
| NAT2*5/*14 | 10 | 10.4 | Slow |
| NAT2*6/*6 | 7 | 7.3 | Slow |
| NAT2*6/*7 | 1 | 1 | Slow |
| NAT2*6/*14 | 4 | 4.2 | Slow |
| Total Lent | 47 | 49 | |
| NAT2*4/*4 | 1 | 1 | Rapid |
| NAT2*4/*5 | 1 | 1 | Rapid |
| NAT2*4/*6 | 7 | 7.3 | Rapid |
| NAT2*4/*12 | 3 | 3.1 | Rapid |
| NAT2*4/*13 | 6 | 6.3 | Rapid |
| NAT2*4/*14 | 2 | 2.1 | Rapid |
| NAT2*5/*12 | 9 | 9.4 | Rapid |
| NAT2*6/*12 | 4 | 4.2 | Rapid |
| NAT2*6/*13 | 4 | 4.2 | Rapid |
| NAT2*7/*13 | 1 | 1 | Rapid |
| NAT2*12/*12 | 1 | 1 | Rapid |
| NAT2*12/*13 | 4 | 4.2 | Rapid |
| NAT2*13/*13 | 1 | 1 | Rapid |
| NAT2*13/*14 | 3 | 3.1 | Rapid |
| Total Rapide | 47 | 49 | |
| NAT2*6/*new (838) | 1 | 1 | Unknown |
| NAT2*5/*12H | 1 | 1 | Unknown |
| Total Unknowna | 2 | 2 | |
| Total | 96 | 100 | |
a
Two out of the 96 tested subjects had an unknown acetylator phenotype as they were composite heterozygotes for a slow-acetylator allele and an allele with unknown functional effect.