Table 2.
Effects of PBA orally administered at dose levels of (50 mg & 200 mg/kg.b.wt.) to dam rats and their first generation females on serum levels of lipid profile, FSH and estrogen hormones. (Mean ± SE) (n = 5).
| Groups | Parameters |
|||||
|---|---|---|---|---|---|---|
| Total cholesterol (mg/dl) | Triglycerides (mg/dl) | HDL (mg/dl) | LDL (mg/dl) | FSH (IU/L) | Estrogen (pg/ml) | |
| Group1 (Control dam) | 90.81±0.58e | 80.57±0.41e | 50.20±0.59a | 30.48±1.02e | 3.71±0.80ab | 26.71±0.25d |
| Group 2 (Dam treated with Low dose of BPA) | 98.21±0.84d | 85.59±0.27d | 46.61±0.41 | 34.41± 0.51d | 3.43±0.32bc | 29.46±0.31c |
| Group 3 (Dam treated with High dose of BPA) | 105.20±0.37c | 88.58±0.23c | 42.46±0.29cd | 45.32± 0.92b | 2.95±0.30d | 31.49±0.55b |
| Group 4 (Control F1 female) | 92.40±0.42e | 82.30±0.58e | 49.35±0.31a | 31.47± 0.36e | 3.87±0.61a | 25.93±0.43d |
| Group 5 (F1 female treated with Low dose of BPA) | 107.80±0.34b | 106.41±0.28b | 43.41± 052c | 41.34± 0.62c | 3.29±0.45c | 30.75±0.53bc |
| Group 6 (F1 female treated with High dose of BPA) | 112.10±0.53a | 108.18±0.72a | 41.23±0.65d | 49.16±0.93a | 2.57±0.41e | 36.66±0.75a |
Means within the same column having the different superscripts are significantly different at (P < 0.05).