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. Author manuscript; available in PMC: 2018 Jul 20.
Published in final edited form as: Stat Med. 2017 Apr 9;36(16):2576–2589. doi: 10.1002/sim.7292

Table 2.

False positive and negative rates of pulse detection and bias and coverage of population means

False Positive Rate (SE) False Negative Rate (SE)
Model Population Single subject Population Single Subject
Reference 7.1% (0.9%) 9.0% (1.1%) 5.7% (1.4%) 6.0% (1.4%)
Short Series 16.4% (0.4%) 30.3% (0.5%) 10.0% (0.4%) 16.9% (0.6%)
Slow Pulsing 4.1% (0.8%) 6.1% (1.0%) 1.9% (0.7%) 2.3% (0.9%)
Small Mass 27.6% (3.1%) 30.2% (3.2%) 30.8% (3.8%) 33.6% (4.1%)
Multia 27.9% (4.3%) 31.8% (4.4%) 27.2% (4.6%) 31.6% (5.0%)
Bias and Coverage of Population Means

Pulse Mass, μa Pulse Width, μw
Population Single Subject Population Single Subject
Model Truth Biasb (SE) Cov.c Bias (SE) Cov. Truth Bias (SE) Cov. Bias (SE) Cov.

Reference 1.25 −0.05 (0.02) 96 −0.08 (0.03) 60 3 −0.1 (0.026) 98 −1.0 (0.06) 55
Short Series 1.25 −0.09 (0.03) 95 −1.18 (0.06) 100 3 −0.30 (0.05) 99 −2.44 (0.08) 87
Slow Pulsing 1.25 −0.09 (0.03) 97 −0.6 (0.03) 54 3 −0.05 (0.03) 96 −1.2 (0.07) 72
Small Mass 0 −0.03 (0.04) 97 −1.0 (0.09) 93 3 −0.3 (0.06) 94 −1.9 (0.09) 89
Multia 0 −0.28 (0.06) 92 −1.5 (0.1) 88 3 −0.27 (0.05) 99 −1.9 (0.10) 92
Baseline, μb Half-life, μh
Population Single Subject Population Single Subject
Model Truth Bias (SE) Cov. Bias (SE) Cov. Truth Bias (SE) Cov. Bias (SE) Cov.

Reference 2.6 −0.001 (0.02) 94 −0.01 (0.02) 30 45 −0.2 (0.09) 97 0.5 (0.1) 93
Short Series 2.6 0.03 (0.02) 95 0.03 (0.02) 74 45 −0.74 (0.23) 98 2.77 (0.30) 95
Slow Pulsing 2.6 −0.03 (0.02) 95 −0.04 (0.02) 9 45 −0.3 (0.09) 99 0.1 (0.1) 96
Small Mass 2.6 0.04 (0.02) 94 0.05 (0.02) 21 45 −0.4 (0.2) 99 2.4 (0.2) 96
Multia 2.6 0.006 (0.02) 98 0.02 (0.02) 19 60 −1.1 (0.3) 94 −2.3 (0.3) 98
a

Low mass and frequency with a longer half-life;

b

average bias of the posterior means;

c

Cov.=Coverage of the 95% credible interval