Fig 6.

Funnel plots demonstrating the accuracy of the APRI (A), FIB-4 (B) and Fibroscan (C) versus the inverse of the square root of the effective sample size (ESS) for the prediction of F2–4 fibrosis. We derived the funnel plot and Egger test to the accuracy of meta-analysis inferences. Continuous lines represent the overall estimates of test accuracy. The Egger test did not detect a significant publication bias (p>0.05). For Fibroscan, the Egger test shows a borderline significant p-value (p = 0.0535) for Fibroscan data, which is driven by an outlier, the study by Carrion et al (2006).