Figure 1.

Measuring intrinsic ignition. A, The activity of a region in the network can be measured using BOLD neuroimaging signals where a threshold method can be used to define events as those crossing a threshold from below (see green line and Materials and Methods). For each driving event, we measure the activity in the rest of the network (in stippled red area) in the gray time window. B, This corresponds to a binary phase lock matrix over the time window (left panel). In this matrix, we can compute the integration by finding the largest subcomponent (computing the area under the curve for all integration values for all thresholds). This integration is a measure of the global integration, i.e., the broadness of communication across the network (Deco et al., 2015). This can be repeated for each of the driving events, producing a mean of the intrinsic ignition for each network region, which we call Ignition-Driven Mean Integration (IDMI).