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Dose-dependent IL-2 responses from B6 and B6HLA mouse splenocytes in response to recombinant streptococcal SAgs. (A) Fifteen percent SDS/PAGE of recombinant streptococcal SAgs. Molecular weight markers are labeled (Left) in kilodaltons. (B and C) SAg activation of B6 and B6HLA mouse splenocytes (2 × 105 cells per well) using the recombinant SAgs shown in A. Mouse IL-2 was measured after 18 h at the indicated SAg concentrations and bars represent the mean ± SEM.
