Table S3.
General demographics and histopathology of patients with pancreatic cancer by CA19-9 status
| Pancreatic cancer with detectable CA19-9, n = 109 | Pancreatic cancer with undetectable CA19-9, n = 112 | P value | |
| Age, y, mean ± SD | 65.9 ± 10.24 | 67.9 ± 10.6 | 0.136 |
| Gender, n (%) | 0.721 | ||
| Male | 61 (50.4) | 60 (49.6) | |
| Female | 48 (48.0) | 52 (52.0) | |
| Race, n (%) | 0.598 | ||
| White | 95 (50.5) | 93 (49.5) | |
| African-American | 2 (50.0) | 2 (50.0) | |
| Hispanic | 1 (100.0) | — | |
| Asian | 7 (58.3) | 5 (41.7) | |
| Other or unknown | 4 (25.0) | 12 (75.0) | |
| Classic symptoms of PDAC, n (%) | 0.690 | ||
| Absent | 21 (46.7) | 24 (53.3) | |
| Present | 88 (50.0) | 88 (50.0) | |
| Abdominal pain, n (%) | 0.207 | ||
| Absent | 58 (45.7) | 69 (54.3) | |
| Present | 51 (54.3) | 43 (45.7) | |
| Jaundice, n (%) | 0.841 | ||
| Absent | 55 (50.0) | 55 (50.0) | |
| Present | 54 (48.7) | 57 (51.3) | |
| Tumor size, cm, median (IQR) | 3.4 (2.5–4.5) | 2.8 (2.1–3.5) | <0.001 |
| Tumor size, n (%) | 0.028 | ||
| ≤ 1.00 cm | — | 2 (100.0) | |
| 1.01–1.50 cm | 6 (27.3) | 16 (72.7) | |
| 1.51–2.00 cm | 4 (33.3) | 8 (66.7) | |
| 2.01–2.50 cm | 20 (42.5) | 27 (57.5) | |
| 2.51–3.00 cm | 17 (44.7) | 21 (55.3) | |
| 3.01–3.50 cm | 21 (58.3) | 15 (41.7) | |
| 3.51–4.00 cm | 13 (59.1) | 9 (40.9) | |
| >4.01 cm | 28 (66.7) | 14 (33.3) | |
| AJCC T stage, n (%) | 0.001 | ||
| T1 | 4 (18.2) | 18 (81.8) | |
| T2 | 18 (39.1) | 28 (60.9) | |
| T3 | 87 (56.9) | 66 (43.1) | |
| AJCC N stage, n (%) | 0.009 | ||
| N0 | 17 (33.3) | 34 (66.7) | |
| N1 | 92 (54.1) | 78 (45.9) | |
| AJCC M stage, n (%) | — | ||
| M0 | 109 (49.3) | 112 (50.7) | |
| M1 | — | — | |
| AJCC stage, n (%) | 0.035 | ||
| IA | 2 (16.7) | 10 (83.3) | |
| IB | 7 (41.2) | 10 (58.8) | |
| IIA | 8 (36.4) | 14 (63.6) | |
| IIB | 92 (54.1) | 78 (45.9) | |
| Grade of tumor differentiation, n (%) | 0.666 | ||
| Well/moderately differentiated | 68 (48.2) | 73 (51.8) | |
| Poorly differentiated | 41 (51.3) | 39 (48.7) | |
| Perineural invasion, n (%) | 0.044 | ||
| Absent | 8 (30.8) | 18 (69.3) | |
| Present | 101 (51.8) | 94 (48.2) | |
| Lymphovascular invasion, n (%) | <0.001 | ||
| Absent | 25 (32.9) | 51 (67.1) | |
| Present | 84 (57.9) | 61 (42.1) | |
| Number of harvested nodes, median (IQR) | 19 (16–26) | 20 (14–29) | 0.973 |
| Number of harvested nodes, n (%) | 0.544 | ||
| ≤20 nodes | 57 (51.3) | 54 (48.7) | |
| >20 nodes | 52 (47.3) | 58 (52.7) | |
| Number of positive nodes, median (IQR) | 3 (1–6) | 2 (0–4) | 0.038 |
| Positive nodes, n (%) | 0.009 | ||
| Absent | 17 (33.3) | 34 (66.7) | |
| Present | 92 (54.1) | 78 (45.9) |