Fig. 2.

DC vaccination with or without PD-1 mAb blockade results in elevated [¹⁸F]-FAC probe accumulation in lymph nodes. (A–D) Representative 3D whole-body reconstructions of [¹⁸F]-FAC PET and CT imaging in control, DCVax, PD-1 mAb, and DCVax + PD-1 mAb treatment groups. (E) Regions of interest (ROIs) and quantification of probe uptake measured in the cervical and axillary lymph nodes in the treatment groups. *P < 0.05; **P < 0.005, unpaired t tests of the ROI data. n = 4–6/group. Measurements were repeated at least twice to verify the results.