Table 3. Association between GLUT1 and clinicalpathological characteristics.
| Variables | No. of studies | No. of patients | Effects model | OR (95%CI) | p | Heterogeneity | Publication bias Begg’s p | |
|---|---|---|---|---|---|---|---|---|
| I2(%) | Ph | |||||||
| Gender (male vs. female) | 5 | 721 | REM | 2.29(1.17-4.49) | 0.015 | 69.5 | 0.011 | 1 |
| Tumor stage (III-IV vs. I - II) | 5 | 885 | FEM | 2.46(1.79-3.38) | <0.001 | 49.7 | 0.093 | 0.221 |
| Age (years, ≥65 vs. <65) | 4 | 606 | FEM | 1.24(0.9-1.72) | 0.19 | 8.9 | 0.349 | 0.734 |
| Histology (SCC vs. adenocarcinoma) | 4 | 616 | FEM | 6.99(4.71-10.38) | <0.001 | 50 | 0.112 | 0.308 |
| Tumor size (≥3cm vs. <3cm) | 3 | 323 | FEM | 2.77(1.73-4.44) | <0.001 | 0 | 0.48 | 1 |
| Differentiation (poor vs. moderate/well) | 3 | 333 | REM | 1.03(0.15-6.96) | 0.976 | 91.8 | <0.001 | 0.602 |
Abbreviations: REM, random-effects model; FEM, fixed-effects model; SCC, squamous cell carcinoma.