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. 2017 May 9;8(37):61001–61010. doi: 10.18632/oncotarget.17720

Figure 5. Tim-3 reverses the ox-LDL-induced decrease of anti-atherogenic cytokines in HUVECs.

Figure 5

(A and B) Quantitation of flow cytometric analysis of production of the indicated cytokines (IL-4, IL-13, IL-5, IL-10, and TGF-β) (A) and master transcription factors associated with Th2 and Treg cells (GATA-3, IRF-4, and FoxP3) (B) in HUVECs after stimulation with or without ox-LDL (10 μg/mL) in the presence or absence of Tim-3 (1,000 ng/mL) or anti-Tim-3 mAb (10 μg/mL). Data represent mean ± SEM. *P < 0.5, **P < 0.01, and ***P < 0.001 compared with the control group.