Table 7. Validation of expression and diagnostic value of eight lncRNAs in LUSC based on GEO dataset (GSE30219).
Variable | pT | LUSC | T-test | ROC | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
n | Mean | SD | n | Mean | SD | t | P | AUC | SE | 95% CI | P | |
FENDRR | 14 | 5.214915 | 0.663845 | 82 | 4.295079 | 0.188372 | 7.254 | <0.0001 | 0.922 | 0.0437 | 0.850 - 0.967 | <0.0001 |
GATA6-AS1 | 14 | 5.846385 | 0.939914 | 82 | 5.972000 | 13.29700 | 5.972 | <0.0001 | 0.903 | 0.0613 | 0.826 - 0.954 | <0.0001 |
LINC00961 | 14 | 6.285801 | 0.370772 | 82 | 5.672997 | 0.255615 | 7.722 | <0.0001 | 0.900 | 0.0555 | 0.822 - 0.952 | <0.0001 |
LINC00968 | 14 | 6.824595 | 1.210060 | 82 | 3.556648 | 0.449696 | 9.988 | <0.0001 | 0.995 | 0.0046 | 0.952 - 1.000 | <0.0001 |
LINC01272 | 14 | 4.693669 | 0.253514 | 82 | 4.351741 | 0.286088 | 4.574 | <0.0001 | 0.817 | 0.0619 | 0.725 - 0.889 | <0.0001 |
LINC01314 | 14 | 4.701564 | 0.272653 | 82 | 4.485906 | 0.155580 | 2.881 | 0.0120 | 0.753 | 0.0918 | 0.655 - 0.836 | 0.0058 |
RP1-78O14.1 | 14 | 5.166360 | 1.060565 | 82 | 3.347113 | 0.398867 | 6.342 | <0.0001 | 0.863 | 0.0883 | 0.778 - 0.925 | <0.0001 |
SFTA1P | 14 | 7.948137 | 1.428409 | 82 | 5.120226 | 0.715006 | 7.254 | <0.0001 | 0.917 | 0.0561 | 0.843 - 0.964 | <0.0001 |
pT: para-noncancerous tissue; LUSC: lung squamous cell carcinoma