Table 5. MDR analysis for the risk of prostate cancer prediction in an Chinese population.
Best interaction models | Cross-validation | Average prediction error |
P-valuea |
---|---|---|---|
rs1468033 | 100/100 | 0.4566 | 0.0001 |
rs2295080 rs1468033 | 100/100 | 0.3451 | p < 0.0001 |
rs17036508 rs2295080 rs1468033 | 100/100 | 0.3434 | p < 0.0001 |
age rs17036508 rs2295080 rs1468033 | 99/100 | 0.4066 | p < 0.0001 |
age rs17036508 rs2295080 rs1468033 rs7250897 | 78/100 | 0.4254 | p < 0.0001 |
BMI smoking_status race rs17036508 rs2295080 rs1468033 | 45/100 | 0.4467 | p < 0.0001 |
smoking_status age race rs17036508 rs2295080 rs1468033 rs7250897 | 61/100 | 0.4022 | p < 0.0001 |
BMI smoking_status age race rs17036508 rs2295080 rs1468033 rs7250897 | 100/100 | 0.5066 | p < 0.0001 |
MDR: multifactor dimensionality reduction.
The best model with maximum cross-validation consistency and minimum prediction error rate was in bold.
aP-value for 1000-fold permutation test.