Figure 4. Wogonoside inhibit hypertrophic conversion and VEGF generation in mice chondrocyte.

(A-B) The protein expression of Col X, RUNX-2, and VEGF-A in chondrocytes treated as above. (C-D) wogonoside ameliorate IL-1β–induced chondrocyte hypertrophy and mineralization (as assessed by AP staining). The data in the figures represent the averages ± S.D. Significant differences between the treatment and control groups are indicated as **P<0.01, *P<0.05, n = 3.