Figure 6. Stathmin overexpression increased ESCC cell lung metastasis in vivo.

(A) ESCC cells were implanted into mouse tail veins, and body weight was measured every two days. Body weight was significantly lower in mice injected with STMN1 cells than in the control group (P<0.001). (B) Statistical results of lung metastasis. (C) After 39 days, the STMN1 cell-injected mice had developed metastatic nodules, whereas the control group had not. (D) After 49 days, both groups of ESCC cell-injected mice developed metastatic nodules, although the lung metastasis area was larger in the STMN1-injected mice.