Table 1. Correlation between serum stathmin levels and clinicalpathological features.

Parameter	Group	N	Levels serum stathmin (ng/ml)	P
			Mean ±SD
ESCC patients		535	5.98±2.89	<0.001
Healthy control		288	2.16±1.19
Lymph nodes metastases
	Yes	221	5.48±2.61	<0.005
	No	248	6.14±2.85
Tumor stage
	I+ II	209	5.72±.72I	<0.05
	III+IV	233	6.40±2.91
Tumor size
	<5cm	158	5.41±2.43	<0.05
	≥5cm	302	6.10±3.00
Pathological grade
	poorly	73	6.25±2.88	0.337
	Moderately	267	5.91±2.91
	well	118	5.89±2.95
Gender
	Male	438	6.18±2.91	<0.001
	Female	97	5.08±2.61
Ages
	≥50	477	5.88±2.86	<0.05
	<50	58	6.78±3.0