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. 2017 Jun 27;8(37):61876–61889. doi: 10.18632/oncotarget.18711

Figure 1. Representative Sanger sequences for each STAT3 mutation found.

Figure 1

By Sanger sequencing, STAT3 mutations were observed in 36 out of 101 T-LGL leukemia patients. Two more cases were found by ARMS-PCR. Upper each graph the cases and their incidence (%) among STAT3 mutated patients (n = 38) are indicated. Y640F and D661Y accounted for the most frequent mutations found.