Table 1. Overview for the characteristics of the cohort.

Clinicopathologic features	Case number	Percentage
Age
≤55 ys	61	38.6%
>55 ys	97	61.4%
Gender
Female	53	33.5%
Male	105	66.5%
Localization
Upper	30	19.0%
Middle	67	42.4%
Lower	61	38.6%
Tumor size
≤5.0 cm	91	57.6%
>5.0 cm	67	42.4%
Invasion depth
T1-T2	54	34.2%
T3-T4	104	65.8%
Differentiation
Well	15	9.5%
Modern	74	46.8%
Poor	69	43.7%
TNM stage
I-II	63	39.9%
III-IV	95	60.1%
SRPK1 expression
Low	75	47.5%
High	83	52.5%