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. 2017 Jul 7;8(37):62081–62098. doi: 10.18632/oncotarget.19060

Figure 5. Quantitative results from effect of BIX01294 on angiogenesis-related protein expression.

Figure 5

SiHa cells were treated with BIX01294 (5 μM) for 4 hrs; after washing out the medium, cells were incubated in fresh culture medium for 24 hrs to collect conditioned medium. Conditioned medium was used for angiogenic factor analysis. Quantitative results are of angiogenic factor expression in SiHa cells (**p < 0.01; ***p < 0.001; ****p < 0.0001). IL-8: interleukin-8. Data are presented as mean ± SD. (BIX01294, n = 3; control, n = 3). Three proteins shown in box had a BIX01294/vehicle ratio of less than 0.5. They were used for gene knockdown and overexpression studies.